A description of eosinophilic esophagitis in the Southwestern state of Nevada. Issue 3 (2nd April 2020)

• Record Type: Journal Article
• Authors: Anderson, Julia; Moonie, Sheniz; Hogan, Mary Beth; Labus, Brian
• Is Part Of: Postgraduate medicine. Volume 132:Issue 3(2020)
• Page Start: 251
• Page End: 255
• Publication Date: 2020-04-02
• Subjects: Eosinophilic esophagitis -- epidemiology -- biostatistics -- demographic analysis -- atopic illness; Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Periodicals; 610.5
• DOI: 10.1080/00325481.2019.1687192
• Languages: English
• ISSNs: 0032-5481

Abstract

ABSTRACT: Objectives: Eosinophilic esophagitis (EoE) is a rare immune-mediated esophageal disorder that has been documented worldwide. Prior to this study, eosinophilic esophagitis had not been described in the Southwestern state of Nevada. Records containing positive eosinophilic esophagitis diagnosis codes were extracted from a large hospital utilization database and yielded over 2, 000 records over 5 years (2013–2017). Methods: Descriptive statistics were used to identify the overall population demography. Logistic regression was used to determine the factors associated with an eosinophilic esophagitis event in Nevada. Results: Males were 2.93 times more likely (95% CI: 2.53, 3.41; p < 0.001) to have had an eosinophilic esophagitis event when compared to females. Older age was also significant; for each additional year in age the odds of having an eosinophilic esophagitis visit increased by 30% (95% CI: 1.28, 1.31; p < 0.001). Finally, individuals living in the Northern region had 1.95 higher odds of an eosinophilic esophagitis event than their Southern counterparts (OR = 1.95, 95% CI: 1.68, 2.26; p < 0.001). Conclusions: The climate in Nevada makes this study novel, as the climate is unlike other studies reporting EoE disease prevalence. Previous atopic studies in Nevada report that warmer, drier weather leads to increased atopic illness and perennial pollen, which ultimately may be contributing to the higher than expected number of EoE records identified. Given the well-documented relationship between EoE and atopy, Nevada may be a susceptible region for this condition and an ideal location for future studies.