Melanocyte Colonization and Pigmentation of Breast Carcinoma: Pathological and Clinical Aspects. (20th December 2012)

• Record Type: Journal Article
• Authors: Mele, Marco; Laurberg, Tinne; Engberg Damsgaard, Tine; Funder, Jonas; Jensen, Vibeke
• Other Names: Miele E. Academic Editor.; Miliaras D. Academic Editor.; Pich A. Academic Editor.; Tsuruta D. Academic Editor.
• Is Part Of: Case reports in pathology. Volume 2012(2012)
• Publication Date: 2012-12-20
• Subjects: Pathology -- Periodicals; Pathology; Pathology; Electronic journals; Periodicals; Periodicals; Case Reports; Fulltext; Internet Resources; Periodicals; 616.07
• DOI: 10.1155/2012/427628
• Languages: English
• ISSNs: 2090-6781

Abstract

Abstract : Introduction . Melanocyte colonization of breast carcinoma by nonneoplastic melanocytes of epidermal origin is a rare and serious condition first described in 1977. We report on the exceptional clinical and pathological features of this migration phenomenon in a 74-year-old patient. Discussion . The pathogenesis by which melanocyte migration takes place is not known, but a breached basement membrane is considered essential. Conclusion . Histological examination and additional staining of skin are essential to differentiate breast cancer melanosis from malignant melanoma.