Does reconstruction affect outcomes following exclusively endoscopic endonasal resection of benign orbital tumors: A systematic review with meta‐analysis. Issue 1 (31st March 2022)

• Record Type: Journal Article
• Authors: Lehmann, Ashton E.; von Sneidern, Manuela; Shen, Sarek A.; Humphreys, Ian M.; Abuzeid, Waleed M.; Jafari, Aria
• Other Names: Gudis David guestEditor.
• Is Part Of: World journal of otorhinolaryngology-head and neck surgery. Volume 8:Issue 1(2022)
• Page Start: 25
• Page End: 35
• Publication Date: 2022-03-31
• Subjects: cavernous hemangioma -- diplopia -- endoscopic endonasal surgery -- enophthalmos -- meningioma -- orbital reconstruction -- orbital tumor -- outcomes -- schwannoma; Otolaryngology; Head -- Surgery; Neck -- Surgery; Periodicals; 617.51
• DOI: 10.1002/wjo2.13
• Languages: English
• ISSNs: 2095-8811

Abstract

Abstract: Objective: As exclusively endoscopic endonasal resection of benign orbital tumors has become more widespread, high‐quality outcomes data are lacking regarding the decision of when and how to reconstruct the medial orbital wall following resection. The goal of this study was to systematically review pertinent literature to assess clinical outcomes relative to orbital reconstruction practices. Methods: Data Sources: PubMed, EMBASE, Web of Science. A systematic review of studies reporting exclusively endoscopic endonasal resections of benign orbital tumors was conducted. Articles not reporting orbital reconstruction details were excluded. Patient and tumor characteristics, operative details, and outcomes were recorded. Variables were compared using χ 2, Fisher's exact, and independent t tests. Results: Of 60 patients included from 24 studies, 34 (56.7%) underwent orbital reconstruction following resection. The most common types of reconstruction were pedicled flaps ( n = 15, 44.1%) and free mucosal grafts ( n = 11, 32.4%). Rigid reconstruction was uncommon ( n = 3, 8.8%). Performance of orbital reconstruction was associated with preoperative vision compromise ( p < 0.01). The tendency to forego orbital reconstruction was associated with preoperative proptosis ( p < 0.001), larger tumor size ( p = 0.001), and operative exposure of orbital fat ( p < 0.001) and extraocular muscle ( p = 0.035). There were no statistically significant differences between the reconstruction and nonreconstruction groups in terms of short‐ or long‐term outcomes when considering all patients. In patients with intraconal tumors, however, there was a higher rate of short‐term postoperative diplopia when reconstruction was foregone ( p = 0.041). This potential benefit of reconstruction did not persist: At an average of two years postoperatively, all patients for whom reconstruction was foregone either had improved or unchanged diplopia. Conclusion: Most outcomes assessed did not appear affected by orbital reconstruction status. This general equivalence may suggest that orbital reconstruction is not a necessity in these cases or that the decision to reconstruct was well‐selected by surgeons in the reported cases included in this systematic review. Abstract : In this systematic review and meta‐analysis of 24 studies reporting exclusively endoscopic endonasal resections of benign orbital tumors, there were no significant difference between the reconstruction and non‐reconstruction groups in terms of short‐ or long‐term outcomes when considering all 60 patients. In the patients with intraconal tumors ( n = 43), however, there was a higher rate of short‐term post‐operative diplopia when reconstruction was foregone. Highlights: Question: Does orbital reconstruction affect outcomes following exclusively endoscopic endonasal resection of benign orbital tumors? Findings: In this systematic review and meta‐analysis of 60 patients included from 24 studies, there were no statistically significant differences between the reconstruction ( n = 34, 56.7%) and non‐reconstruction groups in terms of short‐ or long‐term outcomes when considering all patients. In patients with intraconal tumors, however, there was a higher rate of short‐term (<2 years) post‐operative diplopia when reconstruction was foregone ( p = 0.041). Meaning: Most outcomes assessed did not appear affected by orbital reconstruction status. This general equivalence may suggest that orbital reconstruction is not a necessity in these cases or that the decision to reconstruct was well‐selected by surgeons in the reported cases included in this systematic review.