Successful Handling of Disseminated BCG Disease in a Child with Severe Combined Immunodeficiency. (24th October 2011)

• Record Type: Journal Article
• Authors: Bacalhau, Sílvia; Freitas, Cristina; Valente, Rosalina; Barata, Deolinda; Neves, Conceição; Schäfer, Katrin; Lubatschofski, Annelie; Schulz, Ansgar; Neves, João Farela
• Other Names: Ottenhoff T. Academic Editor.
• Is Part Of: Case reports in medicine. Volume 2011(2011)
• Publication Date: 2011-10-24
• Subjects: Medicine -- Periodicals; Medicine -- Periodicals; Medicine; Case Reports; Periodicals; 610
• DOI: 10.1155/2011/527569
• Languages: English
• ISSNs: 1687-9627

Abstract

Abstract : In high-burden countries, Mycobacterium bovis Bacillus Calmette-Guérin (BCG) vaccine is administered in newborn to prevent severe Mycobacterium tuberculosis infection. Because life-threatening disseminated BCG disease may occur in children with primary immunodeficiency, vaccination strategy against tuberculosis should be redefined in non-high-burden countries. We report the case of a patient with X-linked severe combined immunodeficiency (SCID) who developed disseminated BCG disease, highlighting the specific strategies adopted.