Lasting Differential Effects on Plasticity Induced by Prenatal Stress in Dorsal and Ventral Hippocampus. (10th January 2016)

• Record Type: Journal Article
• Authors: Grigoryan, Gayane; Segal, Menahem
• Other Names: Marrocco Jordan Academic Editor.
• Is Part Of: Neural plasticity. Volume 2016(2016)
• Publication Date: 2016-01-10
• Subjects: Neuroplasticity -- Periodicals; 612.82
• DOI: 10.1155/2016/2540462
• Languages: English
• ISSNs: 2090-5904

Abstract

Abstract : Early life adversaries have a profound impact on the developing brain structure and functions that persist long after the original traumatic experience has vanished. One of the extensively studied brain structures in relation to early life stress has been the hippocampus because of its unique association with cognitive processes of the brain. While the entire hippocampus shares the same intrinsic organization, it assumes different functions in its dorsal and ventral sectors (DH and VH, resp.), based on different connectivity with other brain structures. In the present review, we summarize the differences between DH and VH and discuss functional and structural effects of prenatal stress in the two sectors, with the realization that much is yet to be explored in understanding the opposite reactivity of the DH and VH to stressful stimulation.