Nanoemulsion and Nanogel Containing Eucalyptus globulus Essential Oil; Larvicidal Activity and Antibacterial Properties. (31st August 2022)

• Record Type: Journal Article
• Authors: Alipanah, Hiva; Abdollahi, Abbas; Firooziyan, Samira; Zarenezhad, Elham; Jafari, Mojtaba; Osanloo, Mahmoud
• Other Names: Ghorbani-Dalini Sadegh Academic Editor.
• Is Part Of: Interdisciplinary perspectives on infectious diseases. Volume 2022(2022)
• Publication Date: 2022-08-31
• Subjects: Communicable diseases -- Periodicals; 571.9805
• DOI: 10.1155/2022/1616149
• Languages: English
• ISSNs: 1687-708X

Abstract

Abstract : Eucalyptus globulus essential oil (EGEO) possesses many biological effects such as antibacterial, antifungal, and insecticide properties. In the current study, the chemical composition of EGEO was first investigated using GC-MS analysis. Then, a nanoemulsion and nanogel containing EGEO (EGEO-nanoemulsion and EGEO-nanogel) were prepared. After that, the successful loading of EGEO was confirmed using ATR-FTIR analysis. EGEO-nanoemulsion and EGEO-nanogel with LC50 values of 27 and 32 μ g/mL showed promising efficacies against Anopheles stephensi larvae. Besides, the efficacy of EGEO-nanogel (IC50 187 μ g/mL) was significantly more potent than EGEO-nanoemulsion (IC50 3732 μ g/mL) against Staphylococcus aureus. However, no significant difference was observed in the efficacy of EGEO-nanoemulsion and EGEO-nanogel against Pseudomonas aeruginosa. Natural components, straightforward preparation, and proper efficacy are some of the advantages of EGEO-nanogel; it could be considered for further consideration against other pathogens and mosquito larvae.