Copper-catalyzed direct decarboxylative fluorosulfonylation of aliphatic carboxylic acids. Issue 67 (1st August 2022)

• Record Type: Journal Article
• Authors: Yi, Ji-Tao; Zhou, Xiang; Chen, Qi-Long; Chen, Zhi-Da; Lu, Gui; Weng, Jiang
• Is Part Of: Chemical communications. Volume 58:Issue 67(2022)
• Page Start: 9409
• Page End: 9412
• Publication Date: 2022-08-01
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc03221j
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Herein we report two complementary methods for direct decarboxylative fluorosulfonylation of carboxylic acids by the merging of copper catalysis with different N -centered HAT regents. Abstract : Sulfonyl fluorides are emerging as key structural motifs in organic synthesis, medicinal chemistry, and materials science. Herein we report two efficient and complementary methods for direct decarboxylative fluorosulfonylation of carboxylic acids by the merging of copper catalysis with different N -centered HAT regents. A wide range of structurally diverse sulfonyl fluorides was readily accessed from primary, secondary, and tertiary carboxylic acids in a single step under mild conditions.