Recent Trends of Polymer Mediated Liposomal Gene Delivery System. (27th August 2014)

• Record Type: Journal Article
• Authors: Kundu, Shyamal Kumar; Sharma, Ashish Ranjan; Lee, Sang-Soo; Sharma, Garima; George Priya Doss, C.; Yagihara, Shin; Kim, Do-Young; Nam, Ju-Suk; Chakraborty, Chiranjib
• Other Names: Kaushik Nagendra K. Academic Editor.
• Is Part Of: BioMed research international. Volume 2014(2014)
• Publication Date: 2014-08-27
• Subjects: Medicine -- Periodicals; Biology -- Periodicals; Biotechnology -- Periodicals; Life sciences -- Periodicals; 610.5
• DOI: 10.1155/2014/934605
• Languages: English
• ISSNs: 2314-6133

Abstract

Abstract : Advancement in the gene delivery system have resulted in clinical successes in gene therapy for patients with several genetic diseases, such as immunodeficiency diseases, X-linked adrenoleukodystrophy (X-ALD) blindness, thalassemia, and many more. Among various delivery systems, liposomal mediated gene delivery route is offering great promises for gene therapy. This review is an attempt to depict a portrait about the polymer based liposomal gene delivery systems and their future applications. Herein, we have discussed in detail the characteristics of liposome, importance of polymer for liposome formulation, gene delivery, and future direction of liposome based gene delivery as a whole.