Five‐to‐Seven Carbon Glycols Severely Impair Bioenergetics and Metabolism of Aggressive Lung Cancer Cells. Issue 9 (8th September 2022)

• Record Type: Journal Article
• Authors: Stefanello, Sílvio Terra; Mizdal, Caren Rigon; Azzam, Ihab; Döhlinger, Lilly; Oeckinghaus, Andrea; Shahin, Victor
• Is Part Of: Advanced nanobiomed research. Volume 2:Issue 9(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-09-08
• Subjects: Nanomedicine -- Periodicals; Biomedical engineering -- Periodicals; Biomedical materials -- Periodicals; Nanomedicine; Nanostructures; Bioengineering; Biocompatible Materials; Electronic journals; Periodicals; Periodical; 610.28
• DOI: 10.1002/anbr.202270091
• Languages: English
• ISSNs: 2699-9307

Abstract

Abstract : Lung Cancer Metabolic reprogramming is a hallmark of metastatic lung cancer cells (A549_3R). In article number 2200050, Victor Shahin and co‐workers establish that 5‐7 carbon glycols reduce the A549_3R ATP production by interfering with LDH and mitochondria. The cover image reveals a decline in mitochondrial membrane potential of A549_3R when exposed to 1, 6‐HD.