The Role of Schwann Cells in Cancer. Issue 9 (4th June 2022)

• Record Type: Journal Article
• Authors: Deborde, Sylvie; Wong, Richard J.
• Other Names: Amit Moran guestEditor.
• Is Part Of: Advanced biology. Volume 6:Issue 9(2022)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2022-06-04
• Subjects: cancer -- nerve repair -- reprogramming -- Schwann cells; Molecular biology -- Periodicals; Systems biology -- Periodicals; Biological systems -- Periodicals; Biotechnology -- Periodicals; Bioengineering -- Periodicals; Biomedical engineering -- Periodicals; 660.6
• DOI: 10.1002/adbi.202200089
• Languages: English
• ISSNs: 2701-0198

Abstract

Abstract: Schwann cells (SCs) are the most abundant cell type in the nerves in the peripheral nervous system and compose a family of subtypes that are endowed with a variety of different functions. SCs facilitate the transmission of neural impulses, provide nutrients and protection for neurons, guide axons in nerve repair, and regulate immune functions. In the context of cancer, recent studies have revealed an active role of SCs in promoting cancer cell invasion, modulating immune responses, and transmitting pain sensation. Abstract : Schwann cells (SCs) are the most abundant cell type in peripheral nerves and compose subtypes with different functions. SCs facilitate neural impulse transmission, provide nutrients to neurons, guide axons in nerve repair, and regulate immune functions. In the context of cancer, recent studies have revealed an active role of SCs in promoting cancer invasion, modulating immune responses, and transmitting pain.