Drug Screening Tools: A Spheroid‐Forming Hybrid Gold Nanostructure Platform That Electrochemically Detects Anticancer Effects of Curcumin in a Multicellular Brain Cancer Model (Small 15/2021). Issue 15 (15th April 2021)

• Record Type: Journal Article
• Authors: Suhito, Intan Rosalina; Angeline, Novi; Lee, Kwang‐Ho; Kim, Huijung; Park, Chun Gwon; Luo, Zhengtang; Kim, Tae‐Hyung
• Is Part Of: Small. Volume 17:Issue 15(2021)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2021-04-15
• Subjects: brain cancer -- drug screening -- electrochemical detection -- gold nanostructures -- multicellular spheroids; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202170066
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : In article number 2002436, Tae‐Hyung Kim and co‐workers demonstrate a novel multifunctional hybrid platform that enables spontaneous cancer spheroids formation on the surface and real‐time non‐destructive electrochemical monitoring of spheroid viability simultaneously. The platform allows for mimicking the complex three‐dimensional cellular networks and multicellular characteristics of real solid tumors in vitro, which will be highly useful for high‐throughput anticancer drug screening.