European research networks to facilitate drug research in children. Issue 10 (20th September 2020)

• Record Type: Journal Article
• Authors: Turner, Mark A.; Cheng, Katharine; de Wildt, Saskia; Hildebrand, Heidrun; Attar, Sabah; Rossi, Paolo; Bonifazi, Donato; Ceci, Adriana; Claverol, Joana; Nafria, Begonya; Giaquinto, Carlo
• Other Names: Gacia‐Bournissen Facundo guestEditor.; Rieder Michael guestEditor.
• Is Part Of: British journal of clinical pharmacology. Volume 88:Issue 10(2022)
• Page Start: 4258
• Page End: 4266
• Publication Date: 2020-09-20
• Subjects: drug development -- paediatric -- research infrastructure; Pharmacology -- Periodicals; Drugs -- Periodicals; 615.1
• DOI: 10.1111/bcp.14545
• Languages: English
• ISSNs: 0306-5251

Abstract

Abstract : Paediatric drug development faces several barriers. These include fragmentation of stakeholders and inconsistent processes during the conduct of research. This review summarises recent efforts to overcome these barriers in Europe. Two exemplar initiatives are described. The European Paediatric Translational Research Infrastructure facilitates preclinical research and other work that underpins clinical trials. conect4children facilitates the design and implementation of clinical trials. Both these initiatives listen to the voices of children and their advocates. Coordination of research needs specific effort that supplements work on science, resources and the policy context. Abstract : European research networks facilitate drug research in children