A Co(II) compound: photocatalytic activity and application value in trigeminal neuralgia with minimally invasive interventional therapy guided by CT. Issue 1 (31st December 2022)

• Record Type: Journal Article
• Authors: Wang, Shu-Wen; Li, Ling-Chao
• Is Part Of: Designed monomers and polymers. Volume 25:Issue 1(2022)
• Page Start: 254
• Page End: 260
• Publication Date: 2022-12-31
• Subjects: Co(II) compound -- photocatalysis -- trigeminal neuralgia; Monomers -- Periodicals; Polymers -- Periodicals; Macromolecules -- Periodicals; Polymerization -- Periodicals; 547.7005
• DOI: 10.1080/15685551.2022.2115207
• Languages: English
• ISSNs: 1385-772X

Abstract

ABSTRACT: A new thermostable Co(II)-based compound, namely [Co3 (L)2 (HTEA)2 ]n (1, HL = isonicotinic acid, H3 TEA = triethanolamine), has been successfully synthesized by the isomicotinic acid ligand and HTEA anion. The photocatalytic property of 1 was also investigated, indicating that it shows excellent photocatalytic activity for the degradation of Rhodamine B (MB) solution under the UV light irradiation. For the treatment of trigeminal neuralgia, the content of the inflammatory cytokines released into the trigeminal ganglion tissue fluid was measured with enzyme-linked immunosorbent assay (ELISA) assay. Then, the real-time Reverse Transcription-Polymerase Chain Reaction (RT-PCR) was conducted and the activation of the nuclear factor kappa-B (NF-κB) inflammatory signaling pathway was measured.