Latent pH-responsive ratiometric fluorescent cluster based on self-assembled photoactivated SNARF derivatives. Issue 1 (1st January 2016)

• Record Type: Journal Article
• Authors: Nakata, Eiji; Yukimachi, Yoshihiro; Uto, Yoshihiro; Hori, Hitoshi; Morii, Takashi
• Is Part Of: Science and technology of advanced materials. Volume 17:Issue 1(2016)
• Page Start: 431
• Page End: 436
• Publication Date: 2016-01-01
• Subjects: Self-assembly -- fluorescent material -- ratiometry -- pH indicator -- photoactivation; 30 Bio-inspired and biomedical materials -- 101 Self-assembly / Self-organized materials -- 208 Sensors and actuators; Materials -- Technological innovations -- Periodicals; 620.112
• DOI: 10.1080/14686996.2016.1204888
• Languages: English
• ISSNs: 1468-6996

Abstract

Abstract: We have developed a self-assembled fluorescent cluster comprising a seminaphthorhodafluor (SNARF) derivative protected by a photoremovable o -nitrobenzyl group. Prior to UV irradiation, a colorless and nonfluorescent cluster was spontaneously assembled in aqueous solution. After UV irradiation, the self-assembled cluster remained intact and showed a large enhancement in pH-responsive fluorescence. The unique pH responsive fluorescent cluster could be used as a dual-emissive ratiometric fluorescent pH probe not only in the test tube but also in HeLa cell cultures. Abstract : UF0001