An Ir(III) complex chemosensor for the detection of thiols. Issue 1 (1st January 2016)

• Record Type: Journal Article
• Authors: Mao, Zhifeng; Liu, Jinbiao; Kang, Tian-Shu; Wang, Wanhe; Han, Quan-Bin; Wang, Chun-Ming; Leung, Chung-Hang; Ma, Dik-Lung
• Is Part Of: Science and technology of advanced materials. Volume 17:Issue 1(2016)
• Page Start: 109
• Page End: 114
• Publication Date: 2016-01-01
• Subjects: Iridium(III) complex -- chemosensor -- thiols; 30 Bio-inspired and biomedical materials -- 208 sensors and actuators; Materials -- Technological innovations -- Periodicals; 620.112
• DOI: 10.1080/14686996.2016.1162081
• Languages: English
• ISSNs: 1468-6996

Abstract

Abstract: In this study, we report the use of a cyclometalated luminescent iridium(III) complex for the visualization of thiols. The detection of glutathione (GSH) by complex 1 is achieved through the reduction of its phendione N^N donor, which influences the metal-to-ligand charge-transfer (MLCT) of the complex. Complex 1 produced a maximum threefold luminescence enhancement at 587 nm in response to GSH. The linear detection range of 1 for GSH is between 0.2 and 2 M equivalents of GSH, with a detection limit of 1.67 μM. Complex 1 also displays good selectivity for thiols over other amino acids. Abstract : UF0001