The T4-L1-Hip Axis: Defining a Normal Sagittal Spinal Alignment. Issue 19 (1st October 2022)

• Record Type: Journal Article
• Authors: Hills, Jeffrey; Lenke, Lawrence G.; Sardar, Zeeshan M.; Le Huec, Jean-Charles; Bourret, Stephane; Hasegawa, Kazuhiro; Wong, Hee-Kit; Hey, Hwee Weng Dennis; Liu, Gabriel; Riahi, Hend; Chelli-Bouaziz, Mouna; Kelly, Michael P.
• Is Part Of: Spine. Volume 47:Issue 19(2022)
• Page Start: 1399
• Page End: 1406
• Publication Date: 2022-10-01
• Subjects: sagittal alignment -- pelvic incidence -- lumbar lordosis -- lumbar pelvic angle -- cone of economy -- adult deformity; Spine -- Abnormalities -- Periodicals; Spine -- Diseases -- Periodicals; Spine -- Surgery -- Periodicals; 616.73005
• DOI: 10.1097/BRS.0000000000004414
• Languages: English
• ISSNs: 0362-2436

Abstract

Abstract : Study Design: This is a cross-sectional cohort. Objective: The aim was to describe sagittal plane alignment and balance in a multinational cohort of nondegenerated, asymptomatic adults. Summary of Background Data: Current sagittal alignment targets were developed using correlations between radiographic and quality-of-life measures in spinal deformity patients, rather than disease-free samples leading to relatively poor accounting for variance within a population. Materials and Methods: Sagittal balance was defined using vertebral body tilt and spinopelvic alignment was defined as the vertebral pelvic angles from C2 to L5 (vertebral pelvic angle=vertebral tilt+pelvic tilt). Associations with pelvic incidence (PI) were assessed using linear regression. Multivariable linear regression was used to estimate a normal L1-S1 lordosis, adjusting for PI and the L1 pelvic angle (L1PA). Correlation between the L1 and T4 pelvic angles was assessed to define a normal thoracic alignment conditioned on lumbar alignment. Results: Among 320 volunteers from 4 continents, median age was 37% and 60% were female. C2 tilt was independent of PI with minimal variation. PI was inadequate for estimating a normal lumbar lordosis (L1-S1, r 2 =0.3), but was strongly associated with the lumbar pelvic angles (L1PA, r 2 =0.58). Defining lumbar lordosis as a function of PI and L1PA resulted in high explained variance ( R 2 =0.74) and the T4 pelvic angle had near perfect correlation with the L1PA ( r =0.9). Conclusions: We defined normal sagittal balance and spinopelvic alignment in a disease-free international volunteer cohort. Four parameters are either fixed or directly modifiable in surgery and can define a normal thoracic and lumbar alignment: the L1-S1 lordosis defined as a function of PI and the L1PA; and the T4 pelvic angle is nearly equivalent to the L1PA, aligning the T4-L1-hip axis.