A short-term effect of caffeinated beverages on blood pressure: A meta-analysis of randomized controlled trails. (June 2021)

• Record Type: Journal Article
• Authors: Xu, Zhican; Meng, Qingshu; Ge, Xinyu; Zhuang, Rulin; Liu, Jing; Liang, Xiaoting; Fan, Huimin; Yu, Ping; Zheng, Liang; Zhou, Xiaohui
• Is Part Of: Journal of functional foods. Volume 81(2021)
• Publication Date: 2021-06
• Subjects: Caffeine -- Blood pressure -- RCT -- Meta-analysis; BP blood pressure -- SBP systolic blood pressure -- DBP diastolic blood pressure -- RCT randomized controlled trial -- SD standard deviation -- CIs confidence intervals; Functional foods -- Analysis -- Periodicals; Food -- Biotechnology -- Periodicals; Nutrition -- Periodicals; 613.2
• DOI: 10.1016/j.jff.2021.104482
• Languages: English
• ISSNs: 1756-4646

Abstract

Graphical abstract: Highlights: Caffeinated beverages intake for less than four weeks elevated blood pressure. The acute BP increasing effect was greater in the adolescent than in the adult. Less than 1 week caffeine intake increased BP more markedly than over one week. High-dose caffeine drinking raised DBP and both high and low-dose increased SBP. Abstract: Blood pressure alteration after taking caffeinated beverages is controversial. We performed a meta -analysis to synthesize the evidence on the relation between short time caffeinated beverages consumption and blood pressure from randomized controlled trials. PubMed and Web of Science were systematically searched. Ultimately 11 articles and 470 enrolled subjects were included in the present meta -analysis. Fixed-model was used to assess the relationship between caffeine and blood pressure alteration across all included studies. We found an overall blood pressure elevation of 3.04/2.45 mmHg for short-term (within four weeks) caffeinated beverages intake. In adolescent population, BP increased 5.31/2.26 mmHg. In the adult group, the BP increased 2.67/2.55 mmHg. Less than one week of caffeine consumption increased BP by 5.23/2.14 mmHg. More than one week caffeine consumption elevated BP by 2.62/2.66 mmHg. This meta -analysis indicates the possibility of increase in blood pressure in a young population with caffeinated beverages.