Storage conditions of oxytocin in a tropical climate in a low‐income country. Issue 1 (31st December 2020)

• Record Type: Journal Article
• Authors: de Vries, Ella Larissa; van Tetering, Anne Antonia Cornelia; van der Hout, M. Beatrijs; Derijks, Luc Jozef Johannes; Sseguya, Simon Peter; Namagembe, Imelda; Byamugisha, Josaphat; Oei, S. Guid
• Is Part Of: International journal of gynaecology and obstetrics. Volume 154:Issue 1(2021)
• Page Start: 44
• Page End: 48
• Publication Date: 2020-12-31
• Subjects: low‐income country -- oxytocin -- postpartum hemorrhage -- quality -- storage conditions -- temperature monitoring -- tropical climate -- uterotonic agents; Gynecology -- Periodicals; Obstetrics -- Periodicals; Electronic journals; 618
• DOI: 10.1002/ijgo.13505
• Languages: English
• ISSNs: 0020-7292

Abstract

Abstract: Objective: To establish the storage conditions of oxytocin in a health facility in a low‐income country with a tropical climate, as suboptimal storage may lead to ineffectiveness of drugs essential to prevent and treat postpartum hemorrhage. Methods: At Mulago National Referral Hospital (28 000–33 000 deliveries/year) in Kampala, Uganda, temperature logging Safe‐Rx cards were placed in boxes of oxytocin and in every known storage location. The route of the boxes through the hospital was tracked for 54 days, and storage conditions were observed. Results: Oxytocin was stored within the recommended temperature range (2°C–8°C) 24% of the time. The average temperature measured within the oxytocin boxes was 18.2°C, with a minimum of –2.3°C and maximum of 30.4°C. Six out of twelve known storage places had a refrigerator, but not one location stored medication at the recommended temperature constantly. The average temperature in the storage places ranged from 9.5°C to 27.6°C, with a minimum temperature of 2.3°C and maximum of 30.9°C. Conclusion: Oxytocin is not stored in the recommended temperature range for the majority of time. The presence of refrigerators does not ensure adherence to advised temperature storage conditions. Synopsis: The presence of refrigerators does not ensure adherence to advised temperature storage conditions for oxytocin in a tropical climate low‐income country.