Non‐invasive brain stimulation for dystonia: therapeutic implications. (7th August 2017)

• Record Type: Journal Article
• Authors: Erro, R.; Tinazzi, M.; Morgante, F.; Bhatia, K. P.
• Is Part Of: European journal of neurology. Volume 24:Number 10(2017:Oct.)
• Page Start: 1228
• Page End: e64
• Publication Date: 2017-08-07
• Subjects: current stimulation -- magnetic stimulation -- tDCS -- TMS -- transcranial; Neurology -- Periodicals; Nervous system -- Diseases -- Periodicals; 616.8
• DOI: 10.1111/ene.13363
• Languages: English
• ISSNs: 1351-5101

Abstract

Abstract : Dystonia is characterized by excessive muscle contractions giving rise to abnormal posture and involuntary twisting movements. Although dystonia syndromes are a heterogeneous group of disorders, certain pathophysiological mechanisms have been consistently identified across different forms. These pathophysiological mechanisms have subsequently been exploited for the development of non‐invasive brain stimulation (NIBS) techniques able to modulate neural activity in one or more nodes of the putative network that is altered in dystonia, and the therapeutic role of NIBS has hence been suggested. Here all studies that applied such techniques as a therapeutic intervention in any forms of dystonia, including the few works performed in children, are reviewed and emerging concepts and pitfalls of NIBS are discussed.