Germline and somatic genetic alterations in two first‐degree relatives with appendiceal low‐grade mucinous carcinoma peritonei. Issue 12 (29th September 2020)

• Record Type: Journal Article
• Authors: King, Mary Caitlin; Munoz‐Zuluaga, Carlos; Ledakis, Panayotis; Studeman, Kimberley; Sittig, Michelle; Gushchin, Vadim; Sardi, Armando
• Is Part Of: Clinical case reports. Volume 8:Issue 12(2020)
• Page Start: 3167
• Page End: 3176
• Publication Date: 2020-09-29
• Subjects: appendix cancer -- genetic analysis -- hyperthermic intraperitoneal chemotherapy -- next‐generation sequencing -- pseudomyxoma peritonei; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.3338
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Comparing genetic mutations of first‐degree relatives with appendiceal pseudomyxoma peritonei may explain clinical outcomes and disease pathogenesis. Molecular profiling of mucinous tumors may identify improved treatments to traditional chemotherapy. Abstract : Comparing genetic mutations of first‐degree relatives with appendiceal pseudomyxoma peritonei may explain clinical outcomes and disease pathogenesis. Molecular profiling of mucinous tumors may identify improved treatments to traditional chemotherapy.