Maternal and perinatal outcomes and factors associated with twin pregnancies among preterm births: Evidence from the Brazilian Multicenter Study on Preterm Birth (EMIP). Issue 2 (2nd March 2020)

• Record Type: Journal Article
• Authors: Santana, Danielly S.; Cecatti, Jose G.; Surita, Fernanda G.; Tedesco, Ricardo P.; Passini, Renato; Souza, Renato T.; Lajos, Giuliane J.; Dias, Tabata Z.; Nomura, Marcelo L.; Rehder, Patricia M.; Sousa, Maria H.
• Other Names: Costa Maria L. investigator.; Pacagnella Rodolfo C. investigator.; Marba Sergio T. investigator.; Guinsburg Ruth investigator.; Martinez Francisco E. investigator.; Zotarelli Vilma investigator.; Gurgel Lucio T. investigator.; Feitosa Francisco E. investigator.; Chaves George N. investigator.; Porto Ana M. investigator.; Coutinho Isabela C. investigator.; Barbosa Lima Antonio C. investigator.; Melo Elias F investigator.; Leite Débora F. investigator.; Amorim Melania M. investigator.; Melo Adriana S. O. investigator.; Melo Fabiana O. investigator.; Martins Marília G. investigator.; Nunes Marynea V. investigator.; Paiva Cláudio S. investigator.; Lima Moises D. investigator.; Freire Djacyr M. investigator.; Tristão Edson G. investigator.; Nascimento Denis J. investigator.; Menezes Carlos A. investigator.; Aquino Marcelo investigator.; Vettorazzi Janete investigator.; Senger Cintia E. investigator.; Assumpção Augusta M. B. investigator.; Guedes Marcela A. F. investigator.; Moreira Maria E. L. investigator.; Borges Vera T. investigator.; Maia Filho Nelson L. investigator.; Mathias Jacinta P. investigator.; Souza Eduardo investigator.; Zamarian Ana C. P. investigator.; Quintana Silvana M. investigator.; Melli Patrícia P. S. investigator.; Lotufo Fátima A. investigator.; Uzilin Kaliane investigator.; Zanette Elvira A. investigator.; Andreucci Carla B. investigator.; Oliveira Tenilson A. investigator.; Oliveira Laércio R. investigator.; Santos Marcos A. N. investigator.; Sass Nelson investigator.; Silveira Mirian R. F. investigator.; Coutinho Pedro R. investigator.; Siqueira Luciana investigator.;
• Is Part Of: International journal of gynaecology and obstetrics. Volume 149:Issue 2(2020)
• Page Start: 184
• Page End: 191
• Publication Date: 2020-03-02
• Subjects: Maternal health -- Neonatal outcome -- Perinatal morbidity -- Preterm birth -- Twin pregnancy; Gynecology -- Periodicals; Obstetrics -- Periodicals; Electronic journals; 618
• DOI: 10.1002/ijgo.13107
• Languages: English
• ISSNs: 0020-7292

Abstract

Abstract: Objective: To compare maternal and perinatal outcomes between twin and single preterm births (PTB) and associated factors. Methods: A cross‐sectional multicenter study was conducted in Brazil with 4046 PTBs from April 2011 to July 2012. Causes of PTB, use of tocolytics, corticosteroids, and antibiotics in twin and single pregnancies, and factors possibly associated with twinning were evaluated using χ 2 tests. Maternal and perinatal outcomes were assessed with prevalence ratios (PR). Results: The main cause of PTB in twin pregnancy was spontaneous onset of preterm labor. Tocolytics were more frequently used in twins (26.9% vs 20.2%). Factors associated with PTB in twins were: maternal age >25 years (62.3% vs 53.4%); interpregnancy interval >3 years (39.0% vs 33.4%); no history of PTB (87.4% vs 79.6%); no previous maternal conditions (78.0% vs 73.3%); no alcohol abuse (88.5% vs 84.3%); no drug addiction (97.5% vs 94.5%); and >6 prenatal visits (46.5% vs 37.6%). Twin pregnancies run a 46% higher risk of cesarean delivery, while first and second twins face a 20% higher risk of low birth weight. Twin pregnancies run increased risks for admission to the NICU, cerebral hemorrhage, necrotizing enterocolitis, and any adverse perinatal outcome. Conclusion: Preterm twin birth is associated with low birth weight and worse neonatal outcomes. Abstract : Preterm twin birth is associated with low birth weight and worse neonatal outcomes.