Extensive amyloid deposits in bone marrow aspirate smears. Issue 12 (30th August 2020)

• Record Type: Journal Article
• Authors: Li, Ting Hon Stanford; Wong, Kit Fai; Wong, Wai Shan
• Is Part Of: Clinical case reports. Volume 8:Issue 12(2020)
• Page Start: 3580
• Page End: 3581
• Publication Date: 2020-08-30
• Subjects: amyloidosis; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.3236
• Languages: English
• ISSNs: 2050-0904

Abstract

Abstract: Amyloid light‐chain (AL) amyloidosis is the most common form of systemic amyloidosis. It can cause progressive organ dysfunction and eventually death, mainly due to cardiac involvement. Amyloidosis may rarely present as extensive amorphous, purplish‐blue deposits in marrow aspirate smears. Demonstration of congophilic property and apple‐green birefringence under polarized light in aspirate smears can allow a rapid diagnosis of amyloidosis. Abstract : Amyloid light‐chain (AL) amyloidosis is the most common form of systemic amyloidosis. It can cause progressive organ dysfunction and eventually death, mainly due to cardiac involvement. Amyloidosis may rarely present as extensive amorphous, purplish‐blue deposits in marrow aspirate smears. Demonstration of congophilic property and apple‐green birefringence under polarized light in aspirate smears can allow a rapid diagnosis of amyloidosis.