The musculoskeletal manifestations of haemophilia: a review of the imaging findings. Issue 10 (October 2022)

• Record Type: Journal Article
• Authors: Ray, A.; Colville, J.G.; Hartley, R.; Rowbotham, E.
• Is Part Of: Clinical radiology. Volume 77:Issue 10(2022)
• Page Start: 730
• Page End: 737
• Publication Date: 2022-10
• Subjects: Medical radiology -- Periodicals; Radiotherapy -- Periodicals; Radiotherapy -- Periodicals; Radiology -- Periodicals; Societies, Medical -- Periodicals; Medical radiology; Radiotherapy; Electronic journals; Periodicals; 616.0757
• DOI: 10.1016/j.crad.2022.06.022
• Languages: English
• ISSNs: 0009-9260

Abstract

Abstract : Haemophilia is a common hereditary cause of bleeding diathesis and the musculoskeletal system is frequently affected. Repeated episodes of haemarthrosis initiate a cascade towards haemophilic arthropathy, a disabling and deforming joint disease with both degenerative and inflammatory features, which include articular cartilage loss, bone erosions, and synovitis. Haemophilic pseudotumour and intra-muscular haematoma make up the remainder of the musculoskeletal manifestations of this systemic condition. Radiological assessment is vital in the assessment and follow-up of these haemophilic complications and MRI is the reference standard. This article summarises the radiological findings relevant to the diagnosis and monitoring of this complex patient group.