A computational method for the investigation of burn scars topology based on 3D optical scan. (October 2022)

• Record Type: Journal Article
• Authors: Furferi, Rocco; Governi, Lapo; Pinzauti, Enrico; Profili, Andrea; Puggelli, Luca; Volpe, Yary
• Is Part Of: Computers in biology and medicine. Volume 149(2022)
• Publication Date: 2022-10
• Subjects: 3D scanning -- Burn scars -- Roughness -- Gaussian filtering -- Wavelet filtering; Medicine -- Data processing -- Periodicals; Biology -- Data processing -- Periodicals; 610.285
• DOI: 10.1016/j.compbiomed.2022.105945
• Languages: English
• ISSNs: 0010-4825

Abstract

Abstract: Burn scar treatment is a difficult subject to address since the improper therapy can have a significant impact on people's quality of life. The evaluation of medical therapy over time should be based on objective measurement of the severity of burn scars and their progression. Unfortunately, most clinical assessments of scars are still reliant on physicians' subjective exams of patients. A profitable method to overcome the limitations of subjective assessment could be to leverage 3D scanning technologies. These could be used to retrieve the surface topology of burns. Accordingly, the goal of this study is to provide an objective approach for analysing the surface topology of burn scars using 3D scanning and roughness-based evaluation. In particular, two types of ISO-compliant profile and surface filters (Gaussian and Wavelet) derived from the analysis of roughness in the mechanical sector are implemented to discriminate form from roughness of scars. Once retrieved, the roughness surface is processed to derive a set of statistical parameters describing the scar surface topology. Three case studies were used to derive these parameters (a synthetic surface, an ostrich-skin surface and a set of scars). After the surface's roughness was determined, a comparison between healthy and unhealthy skin could be established. The devised methods prove their effectiveness in correctly retrieving the main surface characteristics of a burn scar. Therefore, by using the proposed method it will be possible to evaluate the effectiveness of medical therapy by comparing the healthy and scarred skin of a single subject. Graphical abstract: Image 1 Highlights: General discussion on ISO surface metrology methods applied on burn scars. 1D and 2D filtering of 2D and 3D signals, i.e. profile and a surface analysis of the area of interest. Definition of the best filtering parameters for 2D Gauss filtering and for 2D Wavelet analysis. Computation of a number of significant statistical parameters describing the burn scar surface morphology. Test on synthetic data, ostrich samples and actual burned skin.