Integrating hereditary breast and ovarian cancer genetic counselling and testing into mainstream clinical practice: Legal and ethical challenges. (October 2022)

• Record Type: Journal Article
• Authors: Charron, Marilou; Kaiser, Beatrice; Dauge, Aurélie; Gallois, Hortense; Lapointe, Julie; Dorval, Michel; Nabi, Hermann; Joly, Yann
• Is Part Of: Critical reviews in oncology/hematology. Volume 178(2022)
• Publication Date: 2022-10
• Subjects: Oncogenetics -- Oncology -- Primary care -- Genetic testing -- Service models in oncogenetics -- Ethical issues -- Legal issues; Oncology -- Periodicals; Hematology -- Periodicals; 616.994
• DOI: 10.1016/j.critrevonc.2022.103797
• Languages: English
• ISSNs: 1040-8428

Abstract

Abstract: Health professionals not specialized in genetics are expected to take an increasing role in genetic services delivery. This article aims to identify legal and ethical challenges related to a collaborative oncogenetics service model, where non-genetic health professionals provide genetic services to patients. Through a scoping literature review, we identified issues to the provision of hereditary breast and ovarian cancer, or other hereditary adult cancers, genetic testing under this model. Concerns that arose in the literature were informed consent, lack of adherence to best practice guidelines, lack of education of non-genetic health professionals on the provision of genetic services, psychological impacts of genetic testing, continuity of care, the complexity of genetic test results, confidentiality, risks of medical mismanagement, and the associated medical responsibility liabilities. Despite these challenges, there is a growing consensus towards the feasibility of cancer genetic testing being undertaken by non-genetic healthcare professionals in a collaborative oncogenetics service model. Highlights: A collaborative oncogenetics service model is feasible and beneficent for patients. Ethical and legal challenges to collaborative oncogenetics service models persist. Educating primary care physicians in genetics will improve hereditary cancer care. Ensuring continuity in a multidisciplinary cancer care setting will improve service.