Clinical effects of the use of the indocyanine green fluorescence imaging technique in laparoscopic partial liver resection. Issue 5 (9th March 2022)

• Record Type: Journal Article
• Authors: Itoh, Shinji; Tomiyama, Takahiro; Morinaga, Akinari; Kurihara, Takeshi; Nagao, Yoshihiro; Toshima, Takeo; Morita, Kazutoyo; Harada, Noboru; Mori, Masaki; Yoshizumi, Tomoharu
• Is Part Of: Annals of gastroenterological surgery. Volume 6:Issue 5(2022)
• Page Start: 688
• Page End: 694
• Publication Date: 2022-03-09
• Subjects: indocyanine green fluorescence imaging -- laparoscopic partial liver resection; Digestive organs -- Surgery -- Periodicals; 617.43
• DOI: 10.1002/ags3.12563
• Languages: English
• ISSNs: 2475-0328

Abstract

Abstract: Aim: This study aimed to clarify the clinical effects of the indocyanine green (ICG)‐fluorescence imaging (FI) technique for determination of liver transection lines during laparoscopic partial liver resection for liver tumors. Methods: This was a retrospective study including 112 patients who underwent laparoscopic partial liver resection for liver tumors. These enrolled patients were divided into an ICG‐FI group (n = 55) and a non‐ICG‐FI group (n = 57) according to the availability of the ICG‐FI. The clinicopathological characteristics of patients between two groups were compared before and after propensity score matching. Results: The ICG‐FI and non‐ICG‐FI groups differed at baseline in terms of ICG retention rate at 15 min. After propensity score matching, two comparable groups of 32 patients each were obtained. The negativity rated of the pathological surgical margins were comparable between the two groups before and after propensity score matching. However, the surgical margins were significantly wider in the ICG‐FI group before and after propensity score matching ( P = .039 and P = .047, respectively). Conclusion: The ICG‐fluorescence imaging technique may offer clinical benefits in terms of a secure surgical margin in laparoscopic partial liver resection. Abstract : Propensity score matching analysis between patients who underwent and those who did not undergo indocyanine green fluorescence imaging demonstrated that the indocyanine green fluorescence imaging technique using near‐infrared light facilitated the attainment of a wide surgical margin from liver tumors during laparoscopic partial liver resection. To the best of our knowledge, this is the first study focusing on laparoscopic partial liver resection to use propensity score matching to show the use of the indocyanine green fluorescence imaging technique is associated with a macroscopically wider surgical margin in patients with liver tumor.