Correlation between urinary incontinence and psychosis in patients with advanced‐stage Parkinson's disease. Issue 6 (2nd September 2020)

• Record Type: Journal Article
• Authors: Nakahara, Keiichi; Kurisaki, Ryoichi; Nakane, Shunya; Sakamoto, Tetsuro; Ikeda, Tokunori; Yamashita, Tetsuji; Uekawa, Kazutoshi; Ando, Yukio
• Other Names: Takeda Atsushi guestEditor.
• Is Part Of: Neurology and clinical neuroscience. Volume 8:Issue 6(2020:Nov.)
• Page Start: 385
• Page End: 389
• Publication Date: 2020-09-02
• Subjects: advanced‐stage -- dyskinesia -- Parkinson's disease -- psychosis -- urinary incontinence; Neurology -- Periodicals; Neurosciences -- Periodicals; 616.8
• DOI: 10.1111/ncn3.12435
• Languages: English
• ISSNs: 2049-4173

Abstract

Abstract: Objective: To clarify the factors associated with psychosis in advanced‐stage Parkinson's disease (PD). Methods: In this observational cross‐sectional study, we reviewed clinical personal records of patients with PD. They were classified as a stage 3 or above on the Hoehn and Yahr scale, and were treated as outpatients or inpatients at our institute between April 1, 2013, and November 30, 2013. A multiple logistic regression analysis was conducted to discriminate PD with psychosis from PD without psychosis. Results: The majority of patients with PD were female (male, 34; female, 57). Median age was 75.0 years (interquartile range: 67.0 to 80.0), and median duration of PD was 9 years (interquartile range: 5.0 to 13.0). Psychosis was diagnosed in 21 patients (23.1%): 19 had hallucinations and five had delusions. A multivariate logistic regression analysis showed that psychosis significantly correlated with the presence of urinary incontinence (UI) and dyskinesia. Conclusion: In advanced‐stage PD, psychosis is related to UI and dyskinesia.