A case of probable cerebral amyloid angiopathy preceded by symmetrical diffusion‐weighted imaging lesions. Issue 5 (2nd July 2019)

• Record Type: Journal Article
• Authors: Nishida, Takashi; Hattori, Takaaki; Yuasa, Tatsuhiko
• Is Part Of: Neurology and clinical neuroscience. Volume 7:Issue 5(2019:Sep.)
• Page Start: 285
• Page End: 287
• Publication Date: 2019-07-02
• Subjects: Alzheimer disease -- cerebral amyloid angiopathy -- cerebrovascular disorders -- dementia -- occipital lobe; Neurology -- Periodicals; Neurosciences -- Periodicals; 616.8
• DOI: 10.1111/ncn3.12310
• Languages: English
• ISSNs: 2049-4173

Abstract

Abstract: Patients who initially have Alzheimer's disease dementia with no or mild cerebral amyloid angiopathy (CAA) might later develop CAA‐related inflammation. We described a 76‐year‐old man with possible Alzheimer's disease dementia and steroid‐responsive probable CAA‐related inflammation. Initial diffusion‐weighted imaging demonstrated symmetrical high signal intensities in the bilateral posterior region, which might suggest ischemia and predilection of CAA pathology for posterior brain regions. Magnetic resonance images thereafter demonstrated asymmetrical cortical swelling in the left temporo‐parieto‐occipital region with leptomeningeal enhancement, which might show subtle cerebrovascular immunological response may influence the subsequent distinct differences.