Effects of trapped-into-solids volatile organic compounds on paper biodeteriogens. (October 2022)

• Record Type: Journal Article
• Authors: Menicucci, Felicia; Palagano, Eleonora; Michelozzi, Marco; Cencetti, Gabriele; Raio, Aida; Bacchi, Alessia; Mazzeo, Paolo P.; Cuzman, Oana A.; Sidoti, Alessandro; Guarino, Salvatore; Basile, Sara; Riccobono, Ornella; Peri, Ezio; Vizza, Francesco; Ienco, Andrea
• Is Part Of: International biodeterioration & biodegradation. Volume 174(2022)
• Publication Date: 2022-10
• Subjects: VOC -- β-cyclodextrin -- Cocrystal -- Solid formulation -- Biodeteriogen -- Antimicrobial activity; Biodegradation -- Periodicals; Bioremediation -- Periodicals; Biodegradation -- Periodicals; Biodégradation -- Périodiques; Biorestauration -- Périodiques; Electronic journals; 620.11223
• DOI: 10.1016/j.ibiod.2022.105469
• Languages: English
• ISSNs: 0964-8305

Abstract

Abstract: Paper items from historical archives and libraries are frequently colonized by biodeteriogens, the management of which is a major concern. Essential oil Volatile Organic Compounds (VOCs) of thymol, carvacrol and eugenol, with high levels of antimicrobial and insect repellent activity, were stabilized within crystalline networks of β-cyclodextrins and phenazine-based cocrystals, as a new tool for the control of paper-degrading agents. These formulations were obtained via solvent-free methodologies and resulted as easy handling powders, suitable for the treatment of paper items by indirect contact. Their antimicrobial activity was evaluated on the following species isolated from a book depository at Forte Belvedere (Florence, IT): Alternaria alternata, Aspergillus sp., Cladosporium sp., Trichoderma orientale, Metschnikowia sp., and Bacillus sp. Both formulates displayed a significant antimicrobial activity in vitro, with cocrystals showing higher efficacy than β-cyclodextrins. The formulates were also tested against the pest Lasioderma serricorne, towards which the cocrystals entrapping carvacrol and thymol exhibited repellent activity. Overall, the phenazine-carvacrol cocrystal was the best-performing formulate, also giving favourable outcomes in terms of antifungal activity in an on-paper in vitro experiment designed to reproduce on a small-scale the critical conditions of an infested archive. These promising results pave the way towards further experimentations of VOC-based solid formulates, to shed light on such products applicability for the preservation of paper items. Graphical abstract: Image 1 Highlights: Volatile organic compounds (VOCs) trapped into β-cyclodextrins and cocrystals. Solid formulates of thymol, carvacrol and eugenol to combat paper biodeteriogens. Powdery formulates releasing VOCs with high antimicrobial activity. VOC-based formulates showing insect repellent activity.