Chemical constituents from the stems of Ephedra equisetina. (October 2022)

• Record Type: Journal Article
• Authors: Zhu, Deng-Hui; Zhang, Jing-Ke; Jia, Ju-Fang; Liu, Juan-Juan; Wei, Jun-Jun; Yang, Meng; Yang, Ying; Li, Meng; Hao, Zhi-You; Zheng, Xiao-Ke; Feng, Wei-Sheng
• Is Part Of: Phytochemistry letters. Volume 51(2022)
• Page Start: 71
• Page End: 74
• Publication Date: 2022-10
• Subjects: Ephedra equisetina Bunge -- Chemical constituents -- Structure elucidation -- Anti-asthmatic effects; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2022.07.005
• Languages: English
• ISSNs: 1874-3900

Abstract

Abstract: Five new compounds, including two naphthalenes (1, 2 ), a phenolic derivative (3 ) and two glycosides (4, 5 ) were isolated from the stems of Ephedra equisetina Bunge. Their chemical structures were identified by spectroscopic analyses (IR, UV, HRESIMS NMR and ECD). An in vitro bioassay suggested that compound 5 possesses potential anti-asthmatic activities. Graphical Abstract: ga1 Highlights: Five previously undescribed compounds were isolated from the stems of E. equisetina . Their structures were elucidated by NMR spectroscopy and mass spectrometry. The absolute configurations were deduced by interpretation of ECD. Anti-asthmatic effects of all of the isolated compounds were evaluated.