A Rare Cause of Upper Gastrointestinal Bleeding: Sarcina ventriculi. Issue 8 (31st August 2022)

• Record Type: Journal Article
• Authors: Worrall, Emily B.; Chhaparia, Anuj; Carpenter, Danielle; Neuschwander-Tetri, Brent A.
• Is Part Of: ACG Case Reports Journal. Volume 9:Issue 8(2022)
• Page Start: e00846
• Publication Date: 2022-08-31
• DOI: 10.14309/crj.0000000000000846
• Languages: English
• ISSNs: 2326-3253

Abstract

ABSTRACT: We describe a patient who presented with hematemesis and was found to have unusually well-demarcated erythematous mucosa with a 2–3 cm irregular nonbleeding necrotic ulcer in the gastric body on esophagogastroduodenoscopy. Biopsy and pathologic examination of the tissue indicated infection with a rare bacterium, Sarcina ventriculi, prompting treatment with an unproven combination of 4 agents: metronidazole, ciprofloxacin, sucralfate, and pantoprazole. Repeat esophagogastroduodenoscopy 8 weeks later revealed complete resolution of the ulceration and surrounding erythema. These results may contribute toward establishing an appropriate therapeutic regimen for future S. ventriculi infections.