Symptom Association for Gastroesophageal Reflux Disease by pH Monitoring After Peroral Endoscopic Myotomy. (25th August 2022)

• Record Type: Journal Article
• Authors: DeWitt, John M.; Kessler, William R.; Wo, John M.; Stainko, Sarah; Perkins, Anthony; Dickason, Destenee; Al-Haddad, Mohammad A.; Siwiec, Robert
• Is Part Of: American journal of gastroenterology. Volume 117:Number 8(2022)
• Page Start: 1316
• Page End: 1319
• Publication Date: 2022-08-25
• Subjects: Stomach -- Diseases -- Periodicals; Intestines -- Diseases -- Periodicals; Gastroenterology -- Periodicals; Gastrointestinal Diseases -- Periodicals; Electronic journals; Periodicals; 616.33
• DOI: 10.14309/ajg.0000000000001801
• Languages: English
• ISSNs: 0002-9270

Abstract

Abstract : INTRODUCTION: There are limited data correlating symptoms with reflux episodes during pH studies after peroral endoscopic myotomy. METHODS: Consecutive patients who underwent POEM followed up ≥6 months later by 48-hour ambulatory wireless pH testing off antisecretory therapy were identified. Reflux symptom association was defined as symptom association probability >95%. RESULTS: The most frequent symptoms of heartburn (47.2%), cough (45.1%), and chest pain (39.6%) were associated with a positive reflux symptom association (symptom association probability >95%) in 20.9%, 17.1%, and 19.4%, respectively. DISCUSSION: There is poor correlation between reported symptoms and esophageal acid exposure during pH testing after POEM.