The Antibiotic Cement Bead Rouleaux: A Technical Trick to Maximize the Surface Area to Volume Ratio of Cement Beads to Improve the Elution of Antibiotics. Issue 9 (September 2022)

• Record Type: Journal Article
• Authors: Perry, Nicholas P.J.; Tucker, Nicholas J.; Hadeed, Michael M.; Heare, Austin; Stacey, Stephen C.; Hammerberg, E. Mark; Mauffrey, Cyril; Parry, Joshua A.
• Is Part Of: Journal of orthopaedic trauma. Volume 36:Issue 9(2022)
• Page Start: 369
• Page End: 373
• Publication Date: 2022-09
• Subjects: antibiotic impregnated cement beads -- surface area -- volume -- osteomyelitis, rouleaux; Orthopedics -- Periodicals; Wounds and injuries -- Periodicals; Orthopedics -- Periodicals; Wounds and Injuries -- therapy -- Periodicals; Periodicals; 617.47044
• DOI: 10.1097/BOT.0000000000002335
• Languages: English
• ISSNs: 0890-5339

Abstract

Summary: The use of antibiotic-impregnated cement as a local antibiotic delivery system is well-established as an adjunctive treatment for chronic osteomyelitis. Because the elution of antibiotics is a surface area phenomenon, the geometry of the cement is an important consideration. The antibiotic cement bead rouleaux technique is a simple and efficient method of bead fabrication that requires only 10 minutes of preparation time and readily available operating room supplies. The discoid structure of the beads provides 3 times the surface-area-to-volume ratio of a spherical bead, which facilitates antibiotic elution. Given the speed and ease of fabrication, along with optimized geometry, the antibiotic cement bead rouleaux is a useful addition to the surgeon's repertoire.