Co-registration of radiotherapy planning and recurrence scans with different imaging modalities in head and neck cancer. (July 2022)

• Record Type: Journal Article
• Authors: Kristensen, Morten Horsholt; Hansen, Christian Rønn; Zukauskaite, Ruta; Johansen, Jørgen; Samsøe, Eva; Maare, Christian; Holm, Anne Ivalu Sander; Eriksen, Jesper Grau
• Is Part Of: Physics and imaging in radiation oncology. Volume 23(2022)
• Page Start: 80
• Page End: 84
• Publication Date: 2022-07
• Subjects: Validation -- Deformable Image Registration -- Head and neck squamous cell carcinoma -- Failure -- CT-MRI; Radiotherapy -- Periodicals; Radiation dosimetry -- Periodicals; Cancer -- Imaging -- Periodicals; Oncology -- Periodicals; 615.842
• DOI: 10.1016/j.phro.2022.06.012
• Languages: English
• ISSNs: 2405-6316

Abstract

Highlights: Head and neck magnetic resonance imaging and computed tomography co-registration. Validation of planning and recurrence scan co-registration separated in time. Mean distances to agreement for regions of interest/normal tissue were tolerable. Abstract: MRI (magnetic resonance imaging) scans are frequently used in follow-up after radiotherapy for head and neck cancer. With the overall aim of enabling MRI-based pattern of failure analysis, this study evaluated the accuracy of recurrence MRI (rMRI) deformable co-registration with planning CT (computed tomography)-scans (pCT). Uncertainty of anatomical changes between pCT and rMRI was assessed by similarity metric analyses of co-registered image structures from 19 patients. Average mean distance to agreement and Dice similarity coefficient performed adequately. Our findings provide proof of concept for reliable co-registration of pCT and rMRI months to years apart for MRI-based pattern of failure analysis.