A bibliometric analysis of research on (R)-ketamine from 2002 to 2021. (1st November 2022)

• Record Type: Journal Article
• Authors: He, Teng; Wang, Di; Wu, Zifeng; Huang, Chaoli; Xu, Xiangyang; Xu, Xiangqing; Liu, Cunming; Hashimoto, Kenji; Yang, Chun
• Is Part Of: Neuropharmacology. Volume 218(2022)
• Publication Date: 2022-11-01
• Subjects: Ketamine -- (R)-Ketamine -- Bibliometric analysis -- Research trends -- Depression; Neuropsychopharmacology -- Periodicals; Autonomic Agents -- Periodicals; Neuropsychopharmacologie -- Périodiques; Neuropsychopharmacology; Periodicals; Electronic journals; 615.78
• DOI: 10.1016/j.neuropharm.2022.109207
• Languages: English
• ISSNs: 0028-3908

Abstract

Abstract: Anesthetic ketamine is a racemic mixture containing equal amount of ( R )-ketamine and ( S )-ketamine. Increasing preclinical data show that ( R )-ketamine has a rapid-onset and sustained antidepressant without significant side effects. There are currently many studies on ( R )-ketamine, however, the quantity and quality of these studies are unknown. Therefore, we conducted a bibliometric analysis of research on ( R )-ketamine from January 2002 to December 2021. We obtained the publications on ( R )-ketamine from the Web of Science database during the period. A variety of bibliographic elements were collected, including annual publications, authors, countries/regions, institutions, journals, and keywords. A total of 922 publications were included in this study. Professor Kenji Hashimoto of Chiba University in Japan was the most productively influential author in the field of ( R )-ketamine and the authors from United States were the leader in this field. In addition, we found that the antidepressant effect of ( R )-ketamine has been a hotspot in very recent years. This study provided a comprehensive analysis of research on ( R )-ketamine and highlighted the growing interest in ( R )-ketamine and its antidepressant effects. Highlights: A total of 922 publications on ( R )-ketamine from January 2002 to December 2021 were analyzed. Professor Kenji Hashimoto of Chiba University was the most productively influential author in the field of ( R )-ketamine. The antidepressant effect of ( R )-ketamine has been a hotspot in recent years.