Resistance training and aerobic training improve muscle strength and aerobic capacity in chronic inflammatory demyelinating polyneuropathy. Issue 1 (15th April 2017)

• Record Type: Journal Article
• Authors: Markvardsen, Lars H.; Overgaard, Kristian; Heje, Karen; Sindrup, Søren H.; Christiansen, Ingelise; Vissing, John; Andersen, Henning
• Is Part Of: Muscle & nerve. Volume 57:Issue 1(2018)
• Page Start: 70
• Page End: 76
• Publication Date: 2017-04-15
• Subjects: aerobic training -- chronic inflammatory demyelinating polyneuropathy -- quality of life -- resistance training -- subcutaneous immunoglobulin; Neuromuscular diseases -- Periodicals; Muscles -- Periodicals; Nerves -- Periodicals; 616.74
• DOI: 10.1002/mus.25652
• Languages: English
• ISSNs: 0148-639X

Abstract

ABSTRACT: Introduction : We investigated the effects of aerobic and resistance exercise in patients with chronic inflammatory demyelinating polyneuropathy (CIDP). Methods : Eighteen CIDP patients treated with subcutaneous immunoglobulin performed 12 weeks of aerobic exercise and 12 weeks of resistance exercise after a run‐in period of 12 weeks without exercise. Three times weekly the participants performed aerobic exercise on an ergometer bike or resistance exercise with unilateral training of knee and elbow flexion/extension. Primary outcomes were maximal oxygen consumption velocity (VO2 ‐max) and maximal combined isokinetic muscle strength (cIKS) of knee and elbow flexion/extension. Results : VO2 ‐max and muscle strength were unchanged during run‐in (−4.9% ± 10.3%, P = 0.80 and −3.7% ± 10.1%, P = 0.17, respectively). Aerobic exercise increased VO2 ‐max by 11.0% ± 14.7% ( P = 0.02). Resistance exercise resulted in an increase of 13.8% ± 16.0% ( P = 0.0004) in cIKS. Discussion : Aerobic exercise training and resistance exercise training improve fitness and strength in CIDP patients. Muscle Nerve 57 : 70–76, 2018