Comparison between surface electrodes and ultrasound monitoring to measure TMS evoked muscle contraction. Issue 5 (25th February 2021)

• Record Type: Journal Article
• Authors: Kaczmarczyk, Isabella; Rawji, Vishal; Rothwell, John C.; Hodson‐Tole, Emma; Sharma, Nikhil
• Is Part Of: Muscle & nerve. Volume 63:Issue 5(2021)
• Page Start: 724
• Page End: 729
• Publication Date: 2021-02-25
• Subjects: amyotrophic lateral sclerosis -- electromyography -- feature tracking -- motor neuron disease -- motor evoked potential -- muscle ultrasound -- transcranial magnetic stimulation; Neuromuscular diseases -- Periodicals; Muscles -- Periodicals; Nerves -- Periodicals; 616.74
• DOI: 10.1002/mus.27192
• Languages: English
• ISSNs: 0148-639X

Abstract

Abstract: Introduction: Transcranial magnetic stimulation (TMS) is widely used to explore cortical physiology in health and disease. Surface electromyography (sEMG) is appropriate for superficial muscles, but cannot be applied easily to less accessible muscles. Muscle ultrasound (mUS) may provide an elegant solution to this problem, but fundamental questions remain. We explore the relationship between TMS evoked muscle potentials and TMS evoked muscle contractions measured with mUS. Methods: In 10 participants, we performed a TMS recruitment curve, simultaneously measuring motor evoked potentials (MEPs) and mUS in biceps (BI), first dorsal interosseous (FDI), tibialis anterior (TA), and the tongue (TO). Results: Resting motor threshold (RMT) measurements and recruitment curves were found to be consistent across sEMG and mUS. Discussion: This work supports the use of TMS‐US to study less accessible muscles. The implications are broad but could include the study of a new range of muscles in disorders such as amyotrophic lateral sclerosis.