Unilateral hypoglossal nerve palsy with asymmetric facial and limb paresis in axonal Guillain–Barré syndrome. Issue 1 (6th August 2015)

• Record Type: Journal Article
• Authors: Yamagami, Mari; Sakurai, Yasuhisa; Hamada, Kensuke; Sugimoto, Izumi; Hatanaka, Yuki; Uchibori, Ayumi; Chiba, Atsuro
• Is Part Of: Neurology and clinical neuroscience. Volume 4:Issue 1(2016:Jan.)
• Page Start: 25
• Page End: 27
• Publication Date: 2015-08-06
• Subjects: acute motor axonal neuropathy -- anti‐ganglioside antibody -- hypoglossal nerve palsy -- multiple cranial nerve palsy -- variant of Guillain–Barré syndrome; Neurology -- Periodicals; Neurosciences -- Periodicals; 616.8
• DOI: 10.1111/ncn3.12023
• Languages: English
• ISSNs: 2049-4173

Abstract

Abstract: We report a 45‐year‐old man with motor axonal Guillain–Barré syndrome who developed left facial nerve palsy, right hypoglossal nerve palsy, and predominantly left‐sided upper limb paresis and left lower limb paresis. Blood examination identified immunoglobulin G antibodies against gangliosides GD1a, GD1b and GQ1b, and GD1b/GD1a and GD1b/GT1b complexes. He was treated with intravenous immunoglobulin (400 mg/kg/day for 5 days) twice, and tongue deviation and facial palsy resolved in 3 months. Unilateral or asymmetric involvement of the cranial and limb nerves represent a variant form of axonal Guillain–Barré syndrome.