Sensory hypo- and hypersensitivity in patients with brain tumors. (3rd July 2022)

• Record Type: Journal Article
• Authors: Ochi, Ryuta; Saito, Shoko; Hiromitsu, Kentaro; Shigemune, Yayoi; Shinoura, Nobusada; Yamada, Ryoji; Midorikawa, Akira
• Is Part Of: Brain injury. Volume 36:Number 8(2022)
• Page Start: 1053
• Page End: 1058
• Publication Date: 2022-07-03
• Subjects: Hypersensitivity -- hyposensitivity -- acquired brain injury -- depression; Brain damage -- Periodicals; Brain -- Wounds and injuries -- Periodicals; Brain Injuries -- Periodicals; 617.481
• DOI: 10.1080/02699052.2022.2110943
• Languages: English
• ISSNs: 0269-9052

Abstract

ABSTRACT: Objectives: Hyper- and hyposensitivity in multiple modalities have been well-documented in subjects with autistic spectrum disorder (ASD) but not in subjects with acquired brain injury (ABI). The purpose of this study was to determine whether subjects with ABI experience altered sensory processing in multiple sensory modalities, and to examine the relationships between impaired sensory processing and the emotional state. Methods and procedures: Sixty-eight patients with brain or spinal cord tumors participated in the study. Cognitive ability and emotional function were tested, and subjective changes were evaluated in two directions (hyper- and hyposensitivity) and five modalities (visual, auditory, tactile, olfactory, and gustatory) at two time points (after disease onset and after surgery). Results: One-fifth of the participants complained of hypersensitivity in the visual domain, and a similar proportion complained of hyposensitivity in the auditory and tactile domains. Additionally, one-third of participants complained of two or more sensory abnormalities after disease onset. A hierarchical regression analysis indicated that auditory and tactile sensory changes predicted a depressive state. Conclusion: In conclusion, multimodal sensory changes occurred in patients with brain tumors, manifesting as hyper- or hyposensitivity. Sensory changes might be related to depressive state, but the results were inconclusive.