Short sleep duration and risk of gestational diabetes. (3rd August 2022)

• Record Type: Journal Article
• Authors: Nicolì, Francesca; Prete, Alessandro; Citro, Fabrizia; Bertolotto, Alessandra; Battini, Lorella; de Gennaro, Giovanni; Del Prato, Stefano; Bianchi, Cristina
• Is Part Of: Gynecological endocrinology. Volume 38:Number 8(2022)
• Page Start: 672
• Page End: 675
• Publication Date: 2022-08-03
• Subjects: Sleep duration -- sleep quality -- gestational diabetes -- GDM; 睡眠时间 -- 睡眠质量 -- 妊娠期糖尿病 -- GDM; Endocrine gynecology -- Periodicals; Generative organs, Female -- Diseases -- Periodicals; 618.1
• DOI: 10.1080/09513590.2022.2089105
• Languages: English
• ISSNs: 0951-3590

Abstract

Abstract: Objective Sleep disturbances and short sleep duration are common in pregnancy and might contribute to the development of hyperglycemia. Therefore, we evaluated the association of sleep disturbances and gestational diabetes (GDM) in a cohort of women. Methods We collected data of 386 women consecutively screened for GDM in 2019 by 75 gr OGTT, according with IDPSG criteria. Pittsburgh Sleep Quality Index (PSQI) questionnaire was used to assess self-reported poor sleep quality (PSQI score >5) and short nocturnal sleep duration (<6 h). Results Of 386 women, 148 (38.3%) had poor sleep quality and 87 (22.5%) short sleep duration. GDM prevalence was 26.9%. There was no difference in GDM prevalence between women with poor or good sleep quality (26% vs. 28%; n.s.), while GDM was more frequent in women with short sleep duration (35.6% vs. 24.4%; p = 0.038). On univariate logistic regression analysis, short sleep duration (OR 1.71; 95%CI: 1.03-2.86; p = 0.039), previous GDM (OR 3.52; 95%CI: 1.83-6.76; p < 0.0001), family history of diabetes (OR 1.96; 95%CI: 1.21-3.91; p = 0.007), pre-pregnancy overweight (OR 1.85; 95%CI: 1.06-3.23; p = 0.031) or obesity (OR 2.56; 95%CI: 1.40-4.70; p = 0.002) were associated to GDM. However, after adjustment for confounders, short sleep duration did not persist as an independent risk factor for GDM (OR: 1.55; 95%CI: 0.91-2.65; ns). Conclusions Sleep disturbances are relative common among pregnant women. Although GDM seems more common among women with short sleep duration, this sleep disturbance does not seem to be an independent risk factor for GDM in women at high risk.