Endocarditis Caused by Nontypeable Streptococcus pneumoniae . (2nd February 2022)

• Record Type: Journal Article
• Authors: Henriet, Stefanie S V; Langereis, Jeroen D; Lo, Stephanie W; Bentley, Stephen; Mesman, Rob J; Fejzic, Zina; van Niftrik, Laura; van Sorge, Nina M; Wertheim, Heiman F L; de Jonge, Marien I; Cremers, Amelieke J H
• Is Part Of: Clinical infectious diseases. Volume 75:Number 4(2022)
• Page Start: 719
• Page End: 722
• Publication Date: 2022-02-02
• Subjects: infective endocarditis -- Streptococcus pneumoniae -- bacterial polysaccharide capsule -- pathogenesis; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciac079
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae . In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.