Does the subepithelial connective tissue graft in conjunction with a coronally advanced flap remain as the gold standard therapy for the treatment of single gingival recession defects? A systematic review and network meta‐analysis. Issue 9 (12th May 2022)

• Record Type: Journal Article
• Authors: Chambrone, Leandro; Botelho, João; Machado, Vanessa; Mascarenhas, Paulo; Mendes, José João; Avila‐Ortiz, Gustavo
• Is Part Of: Journal of periodontology. Volume 93:Issue 9(2022)
• Page Start: 1336
• Page End: 1352
• Publication Date: 2022-05-12
• Subjects: gingival recession -- surgery -- surgical flaps -- tissue grafts -- wound healing; Periodontics -- Periodicals; 617.632
• DOI: 10.1002/JPER.22-0167
• Languages: English
• ISSNs: 0022-3492

Abstract

Abstract: Background: The aim of this systematic review and network meta‐analysis (NMA) was to assess the efficacy of a bilaminar root coverage technique consisting of the combination of an autogenous subepithelial connective tissue graft (SCTG) and a coronally advanced flap (CAF) compared with the five most indicated alternative approaches for the treatment of single gingival recession defects (GRD). Methods: The protocol of this PRISMA 2020‐compliant systematic review was registered in PROSPERO (CRD42020221362). Three electronic databases were searched up to September 30, 2021 to identify randomized controlled trials that involved the treatment of single GRD without interproximal tissue loss via root coverage procedures. A frequentist NMA was conducted for complete root coverage (CRC), mean root coverage (MRC), and keratinized tissue width (KTW) changes. Results: A total of 38 studies reporting on 830 patients and 1, 265 GRD were included. SCTG + CAF was ranked as the most efficient treatment approach for MRC, CRC, and KTW gain at 6 and 12 months after surgery, except for MRC at the 12‐month follow‐up where enamel matrix derivative plus CAF exhibited superior results. Conclusions: SCTG + CAF can be considered the gold standard for the treatment of single GRD.