Biosensors and biomarkers for determining gestational diabetes mellitus and jaundice in children. (12th June 2021)

• Record Type: Journal Article
• Authors: Peng, Shuangqin; Wang, Qin; Xiong, Guoping; Gopinath, Subash C.B.; Lei, Gang
• Is Part Of: Biotechnology and applied biochemistry. Volume 69:Number 4(2022)
• Page Start: 1354
• Page End: 1364
• Publication Date: 2021-06-12
• Subjects: blood sugar -- glucose biosensor -- liver disease -- nanobiosensor; Biotechnology -- Periodicals; Biochemical engineering -- Periodicals; Biochemistry -- Periodicals; Biochemistry -- Periodicals; Genetic Techniques -- Periodicals; Microbiological Techniques -- Periodicals; 660.6
• DOI: 10.1002/bab.2208
• Languages: English
• ISSNs: 0885-4513

Abstract

Abstract: Gestational diabetes and jaundice are the correlated diseases predominantly found in mother and newborn child. Jaundice is a neonatal complication with an increased risk when mother has gestational diabetes. Mothers with diabetes at an early stage of gestational age are at higher risk for hyperbilirubinemia (jaundice) and hypoglycemia. So, it is mandatory to monitor the condition of diabetes and jaundice during the pregnancy period for a healthy child and safest delivery. On the other hand, nanotechnology has displayed a rapid advancement that can be implemented to overcome these issues. The development of high‐performance diagnosis using appropriate biomarkers provides their efficacy in the detection gestational diabetes and jaundice. This review covers the aspects from a fast‐developing field to generate nanosensors in the nanosized dimensions for the applications to overcome these complications by coupling diagnostics with biomarkers. Further, the serum‐based biomarkers have been discussed for these inborn complications and also the diagnosis with the current trend.