Dual-channel lanthanide-doped nanoprobe for reliable multi-signal ratiometric detection of H2S in whole blood. Issue 69 (9th August 2022)

• Record Type: Journal Article
• Authors: Wei, Zheng; Cao, Tianqi; Li, Luoyuan; Zhu, Xingjun; Zhou, Jing; Liu, Yuxin
• Is Part Of: Chemical communications. Volume 58:Issue 69(2022)
• Page Start: 9642
• Page End: 9645
• Publication Date: 2022-08-09
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d2cc03360g
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A multi-signal method eliminates the influence of the wavelength-dependent absorbance of whole-blood samples, ensuring high diagnostic precision in medical practice. Abstract : Wavelength-dependent absorbance of blood has impeded the development of fluorescence biodetection in whole blood. Here, by replacing the fluorescence working signal with a temperature signal, reliable H2 S detection was performed in samples of whole blood. The developed system was based on a dual-channel lanthanide-doped nanoprobe, which further allowed precise serodiagnosis of acute pancreatitis.