AB0931 Brucellar Spondylodiscitis – a Case Series Analysis. (9th June 2015)

• Record Type: Journal Article
• Authors: Kaffel, D.; Aouadi, A.; Cherif, I.; Hamdi, W.; Zouch, I.; Kchir, M.M.
• Is Part Of: Annals of the rheumatic diseases. Volume 74(2015)Supplement 2
• Page Start: 1211
• Page End: 1211
• Publication Date: 2015-06-09
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2015-eular.6057
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Brucellar spondylitis is rare. It is also the most prevalent clinical form of osteoarticular involvement in adults infected by Brucella. Objectives: The aim of this study was to report the clinical, biological, radiological and therapeutic features of brucellar spondylodiscitis. Methods: Retrospective study including 6 patients followed up in our department between 2006 and 2014. Results: We studied 6 cases (5 of them are male) with a mean age of 55.3 years old [20 - 83]. 3 patients were consumers of unpasteurized milk. The median delay of consultation was 6 months. All patients had fever, night sweats and generalized weakness. Lumbar spine was affected in 4 cases and cervical spine in 2 cases. Neurologic examination was normal in 5 cases, 1 patient had neurologic deficiency. Plain radiographs revealed narrowing of disc spaces in 5 cases and erosion of the antero-upper corner of the body of vertebra in 1 case. MRI was performed in all cases and revealed features suggesting spondylodiscitis in all patients. Epidural inflammation was found in 4 cases. Disco vertebral biopsy was performed in 1 patient revealing a nonspecific histological appearance and an inconclusive bacteriological study. Laboratory tests including CRP, sedimentation rate and leucocytes were increased in all cases. Rose-Bengale test and Wright test were positive in all of them. They were treated with double antibiotics (Rifadine and Cycline), during an average of 4 months in all cases. All of them had in immobilisation and also had a favourable development. Conclusions: Brucellar spondylodiscitis may be difficult to diagnose and have an acute or chronic course. Only rapid and correct management may prevent irreversible neurologic deficits and spinal deformities. Disclosure of Interest: None declared