AB0266 Association of Health Assessment Questionnaire with Range of Motion of Large Joints in Patients with Rheumatoid Arthritis. (9th June 2015)

• Record Type: Journal Article
• Authors: Motomura, H.; Matsushita, I.; Kaneko, A.; Kanbe, K.; Arai, K.; Kuga, Y.; Abe, A.; Matsumoto, T.; Nakagawa, N.; Nishida, K.; Kimura, T.
• Is Part Of: Annals of the rheumatic diseases. Volume 74(2015)Supplement 2
• Page Start: 981
• Page End: 981
• Publication Date: 2015-06-09
• Subjects: Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2015-eular.3672
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Health Assessment Questionnaire (HAQ) is often used to assess functional disabilities, and is closely associated with disease activity and radiographic joint damage in patients with rheumatoid arthritis (RA) 1 . Joint range of motion (ROM) is also affected by inflammation and joint destruction in RA. However, the relationship between HAQ and large joint ROM still remains. Objectives: To examine the association of HAQ with clinical parameters including ROM of large joints in patients with RA. Methods: We have examined 62 patients with RA that were resistant to disease-modifying anti-rheumatic drugs (DMARDs). The mean age was 58.7 years and mean disease duration was 10.2 years. We measured ROM of cervical spine and large joints (bilateral shoulder, elbow, hip, knee and ankle joints), CRP, MMP-3 DAS28-ESR, SDAI, CDAI, degree of large joint damage (ARASHI status score 2 and HAQ. Correlations of parameters were estimated by Spearman's rank correlation coefficient. Differences were considered significant if two-sided P-values were <0.05. Results: HAQ was well correlated with DAS28-ESR, SDAI and CDAI as expected. HAQ was not correlated with total ARASHI status score. However, HAQ was significantly correlated with shoulder flexion (r=0.38, P<0.01), shoulder abduction (r=0.37, P<0.01), elbow flexion (r=0.28, P<0.05) and ankle plantar flexion (r=0.27, P<0.05). Conclusions: We showed that HAQ was associated with ROM of large joint in patients with RA. Specifically, shoulder, elbow and ankle plantar flexion were important determinants of HAQ and, therefore, should be monitored to guide treatment. References: Drossaers-Bal KW, et al. Arthritis Rheum. 1999; 42; 1854-1860. Kaneko A, Matsushita I, et al. Mod Rheumatol. 2013; 23; 1053-1062. Disclosure of Interest: None declared