Cortical collateralization induced by language and arithmetic in non-right-handers. (March 2020)

• Record Type: Journal Article
• Authors: Nakai, Tomoya; Okanoya, Kazuo
• Is Part Of: Cortex. Volume 124(2020)
• Page Start: 154
• Page End: 166
• Publication Date: 2020-03
• Subjects: Functional magnetic resonance imaging -- Laterality -- Inferior frontal gyrus -- Language -- Arithmetic; Neuropsychology -- Periodicals; Nervous system -- Periodicals; Neurology -- Periodicals; Psychophysiology -- Periodicals; Behavior -- Periodicals; Neurology -- Periodicals; 612.825
• DOI: 10.1016/j.cortex.2019.11.009
• Languages: English
• ISSNs: 0010-9452

Abstract

Abstract: The functional overlap of language and arithmetic is debatable. Although some studies have reported independent representations of arithmetic and language in the brain, other studies have reported shared activity of the two cognitive domains in the inferior frontal gyrus. Although most previous studies have evaluated right-handed individuals, variability of hemispheric dominance in non-right-handed individuals should provide important information on the functional collateralization of these two cognitive domains. The present study evaluated the cortical lateralization patterns of the two cognitive domains using functional magnetic resonance imaging in 30 non-right-handed participants who performed language and arithmetic tasks. We found that language and arithmetic tasks demonstrated shared activity in the bilateral inferior frontal gyrus (IFG). Furthermore, the lateralization patterns of language and arithmetic tasks were correlated with each other. Most participants with language dominance in the left hemisphere also exhibited dominance of arithmetic tasks in the left hemisphere; similarly, most participants with language dominance in the right hemisphere exhibited dominance of arithmetic tasks in the right hemisphere. Among all the brain regions, the precentral gyrus, which is located slightly posterior to the IFG, exhibited the highest correlation coefficient between laterality indices of language and arithmetic tasks. These results suggest a shared functional property between language and arithmetic in the brain.