Antisolvent crystallization intensified by a jet crystallizer and a method for investigating crystallization kinetics. (16th January 2020)

• Record Type: Journal Article
• Authors: Wu, Bin; Li, Jing; Li, Chunhui; He, Jinxuan; Luo, Peicheng
• Is Part Of: Chemical engineering science. Volume 211(2020)
• Publication Date: 2020-01-16
• Subjects: Antisolvent crystallization -- Jet crystallizer -- Kinetics -- Population balance equation (PBE) -- Plug flow model (PFM) -- CFD; Chemical engineering -- Periodicals; Génie chimique -- Périodiques; Chemical engineering; Periodicals; Electronic journals; 660
• DOI: 10.1016/j.ces.2019.115259
• Languages: English
• ISSNs: 0009-2509

Abstract

Highlights: Antisolvent crystallization process is intensified by a jet crystallizer. Several microns of NaCl crystals with narrow CSD are prepared. A new definition of supersaturation considering antisolvent/solvent ratio is proposed. Kinetic parameters of nucleation and crystal growth are estimated. Efficient mixing makes the crystallization independent on the mixing due to low Da number. Abstract: In this study, the antisolvent crystallization of NaCl in water-ethanol binary solvent mixtures in a multi-orifice-impinging transverse (MOIT) jet crystallizer is studied both experimentally and numerically. Plug flow model coupled with population balance equation (PFM-PBE) is employed for the estimation of nucleation and crystal growth rate parameters at different supersaturation levels. Computational fluid dynamics coupled with population balance equation (CFD-PBE) is used to evaluate the macromixing and micromixing effect on the crystallization process. It is found that several microns NaCl crystals with narrow crystal size distribution (CSD) are prepared. The mixing process of the antisolvent and the solution is intensified by the MOIT jet crystallizer so that the mixing effect becomes insignificant due to a small Da number. The crystallization kinetics have also been obtained and confirmed by combining PFM-PBE and CFD-PBE approaches with the experiments.