Boron-containing bioactive glasses in bone and soft tissue engineering. Issue 3 (March 2018)

• Record Type: Journal Article
• Authors: Balasubramanian, Preethi; Büttner, Teresa; Miguez Pacheco, Valentina; Boccaccini, Aldo R.
• Is Part Of: Journal of the European Ceramic Society. Volume 38:Issue 3(2018)
• Page Start: 855
• Page End: 869
• Publication Date: 2018-03
• Subjects: Bioactive glasses -- Borosilicate -- Borate -- Bioactivity -- Osteogenesis -- Angiogenesis -- In vivo; Ceramic materials -- Periodicals; Composite materials -- Periodicals; Matériaux céramiques -- Périodiques; Composites -- Périodiques; Ceramic materials; Composite materials; Periodicals; Electronic journals; 666.05
• DOI: 10.1016/j.jeurceramsoc.2017.11.001
• Languages: English
• ISSNs: 0955-2219

Abstract

Abstract: Boron is considered to influence the performance of several metabolic enzymes and boron deficiency is associated with impaired growth and abnormal bone development. As such, boron is a beneficial bioactive element for animals and humans. It is also well known that boron stimulates wound healing and improves bone health. The addition of boron in different proportions to bioactive glasses has significant effects on glass structure, glass processing parameters, biodegradability, biocompatibility, bioactivity and cytotoxicity. Different compositions of bioactive glasses (BGs) containing boron, including boron-doped, borosilicate and borate glasses, are being investigated for bone and soft tissue engineering under the premise that these BGs are suitable carriers of boron, indicating controlled release of B species in the biological environment. This paper reviews up to date research and applications of borate, borosilicate, and boron doped silicate and phosphate BGs focussing on their physical, structural, degradation and biological properties for hard and soft tissue regeneration.