Prevalence of comorbidities and evaluation of their screening in spondyloarthritis: results of the international cross-sectional ASAS-COMOSPA study. Issue 6 (21st October 2015)

• Record Type: Journal Article
• Authors: Moltó, Anna; Etcheto, Adrien; van der Heijde, Désirée; Landewé, Robert; van den Bosch, Filip; Bautista Molano, Wilson; Burgos-Vargas, Ruben; Cheung, Peter P; Collantes-Estevez, Eduardo; Deodhar, Atul; El-Zorkany, Bassel; Erdes, Shandor; Gu, Jieruo; Hajjaj-Hassouni, Najia; Kiltz, Uta; Kim, Tae-Hwan; Kishimoto, Mitsumasa; Luo, Shue-Fen; Machado, Pedro M; Maksymowych, Walter P; Maldonado-Cocco, José; Marzo-Ortega, Helena; Montecucco, Carlo-Maurizio; Ozgoçmen, Salih; van Gaalen, Floris; Dougados, Maxime
• Other Names: Allali Fadoua author non-byline.; González Raquel Almodovar author non-byline.; Blanco-Morales Elena Alonso author non-byline.; Alvarellos Alejandro author non-byline.; Espinar Maria Aparicio author non-byline.; Atagunduz Pamir author non-byline.; Bakker Pauline author non-byline.; Barreira Juan C. author non-byline.; Benbrahim Leila author non-byline.; Benchekroun Bahia author non-byline.; Berman Alberto author non-byline.; Braun Juergen author non-byline.; Cantagrel Alain author non-byline.; Caporali Roberto author non-byline.; Carvalho Pedro author non-byline.; Casado Gustavo author non-byline.; Wei James Cheng-Chung author non-byline.; Colombres Francisco author non-byline.; Mendieta Eugenio del Miguel author non-byline.; Diaz-Garcia Juan D. author non-byline.; de Medicina Escuela Superior author non-byline.; De Bandt Michel author non-byline.; Duarte Vanesa author non-byline.; Carballido Cristina Fernandez author non-byline.; Espartero Mari Cruz Fernandez author non-byline.; Fernandez-Prada Manuel author non-byline.; Flipo Rene-Marc author non-byline.; Ugalde Pilar Font author non-byline.; Gaudin Philippe author non-byline.; Goupille Philippe author non-byline.; Cánovas Dolors Grados author non-byline.; Masmitjá Jordi Gratacós author non-byline.; Grosso Vittorio author non-byline.; Ichikawa Naomi author non-byline.; Inoue Hisashi author non-byline.; Kaneko Yuko author non-byline.; Kawasaki Taku author non-byline.; Kobayashi Shigeto author non-byline.; Lahiri Manjari author non-byline.; Maldonado-Ficco Hernán author non-byline.; Martínez Alejandro author non-byline.; Matsui Kazuo author non-byline.; Esteban Ramón Mazzuchelli author non-byline.; Micelli Corinne author non-byline.; Min Chisun author non-byline.; Morita Mitsuhiro author non-byline.; Mendoza Juan Mulero author non-byline.; Pons Jose Raul Noguera author non-byline.; Okada Masato author non-byline.; Ortiz Alberto author non-byline.; Packham Jon author non-byline.; Pendón Gisela author non-byline.; Pereira Dora author non-byline.; da Silva José A Pereira author non-byline.; Pimentel-Santos Fernando author non-byline.; Rkain Hanan author non-byline.; Rillo Oscar author non-byline.; Lozano Carlos Rodriguez author non-byline.; Ruyssen-Witrand Adeline author non-byline.; Salas Adrián author non-byline.; Salinas-Ramos Carlos author non-byline.; Santosa Amelia author non-byline.; Saraux Alain author non-byline.; Sengupta Raj author non-byline.; Siebert Stefan author non-byline.; Soubrier Martin author non-byline.; Spiegel Caroline author non-byline.; Stolwijk Carmen author non-byline.; Tada Kurisu author non-byline.; Takizawa Naoho author non-byline.; Taniguchi Yoshinori author non-byline.; Taniguchi Atsuo author non-byline.; Chou Chung Tei author non-byline.; Teoh Lay-Keng author non-byline.; Tomita Tetsuya author non-byline.; Tsai Wen-Chan author non-byline.; Tsuji Shigeyoshi author non-byline.; Tsyplenkova Olga author non-byline.; van Tubergen Astrid author non-byline.; Vakil-Gilani Kiana author non-byline.; Valle-Oñate Rafael author non-byline.; Varkas Gaelle author non-byline.; Villaverde Virginia author non-byline.; Yap Ai author non-byline.; Montejo Pedro Zarco author non-byline.;
• Is Part Of: Annals of the rheumatic diseases. Volume 75:Issue 6(2016)
• Page Start: 1016
• Page End: 1023
• Publication Date: 2015-10-21
• Subjects: Spondyloarthritis -- Epidemiology -- Cardiovascular Disease -- Osteoporosis -- Infections; Rheumatism -- Periodicals; 616.723005
• DOI: 10.1136/annrheumdis-2015-208174
• Languages: English
• ISSNs: 0003-4967

Abstract

Abstract : Background: Increased risk of some comorbidities has been reported in spondyloarthritis (SpA). Recommendations for detection/management of some of these comorbidities have been proposed, and it is known that a gap exists between these and their implementation in practice. Objective: To evaluate (1) the prevalence of comorbidities and risk factors in different countries worldwide, (2) the gap between available recommendations and daily practice for management of these comorbidities and (3) the prevalence of previously unknown risk factors detected as a result of the present initiative. Methods: Cross-sectional international study with 22 participating countries (from four continents), including 3984 patients with SpA according to the rheumatologist. Statistical analysis: The prevalence of comorbidities (cardiovascular, infection, cancer, osteoporosis and gastrointestinal) and risk factors; percentage of patients optimally monitored for comorbidities according to available recommendations and percentage of patients for whom a risk factor was detected due to this study. Results: The most frequent comorbidities were osteoporosis (13%) and gastroduodenal ulcer (11%). The most frequent risk factors were hypertension (34%), smoking (29%) and hypercholesterolaemia (27%). Substantial intercountry variability was observed for screening of comorbidities (eg, for LDL cholesterol measurement: from 8% (Taiwan) to 98% (Germany)). Systematic evaluation (eg, blood pressure (BP), cholesterol) during this study unveiled previously unknown risk factors (eg, elevated BP (14%)), emphasising the suboptimal monitoring of comorbidities. Conclusions: A high prevalence of comorbidities in SpA has been shown. Rigorous application of systematic evaluation of comorbidities may permit earlier detection, which may ultimately result in an improved outcome of patients with SpA.